2-Amino-5-methylpyridine → HCID 178423228, compound

HRID 223862Notes

Reaction equation

HRID 223862 reaction equation
CC1=CC=C(N)N=C1.[C-]#[N+]C1CCCCC1.FC1=C(C=O)C(=CC(=C1)C(F)(F)F)C(F)(F)F>>CC1=CN2C(C=C1)=NC(=C2NC1CCCCC1)C1=C(F)C=C(C=C1C(F)(F)F)C(F)(F)F

Participants

6

Reactant 3

HCID 153482-Amino-5-methylpyridineHCID 79129Cyclohexyl isocyanideHCID 467374972-Fluoro-4,6-bis(trifluoromethyl)benzaldehyde

Product 1

HCID 178423228HCID 178423228, compoundYield 5.055%

Reagents, catalysts & solvents 2

HCID 6422Trifluoroacetic acidCatalystHCID 3776IsopropanolSolvent2×

Conditions

Temperature
22 °C

Sources & evidence

ORD record
ord-716e941d3e334df2be1e197eafd55afa
Source dataset
Imidazopyridines dataset

Reaction notes

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