2-Amino-5-methylpyridine → HCID 178422454, compound

HRID 223867Notes

Reaction equation

HRID 223867 reaction equation
CC1=CC=C(N)N=C1.[C-]#[N+]C1CCCCC1.CC1=CC(Br)=C(F)C(C=O)=C1>>CC1=CN2C(C=C1)=NC(=C2NC1CCCCC1)C1=CC(C)=CC(Br)=C1F

Participants

6

Reactant 3

HCID 153482-Amino-5-methylpyridineHCID 79129Cyclohexyl isocyanideHCID 532166923-Bromo-2-fluoro-5-methylbenzaldehyde

Product 1

HCID 178422454HCID 178422454, compoundYield 51.723%

Reagents, catalysts & solvents 2

HCID 6422Trifluoroacetic acidCatalystHCID 3776IsopropanolSolvent2×

Conditions

Temperature
22 °C

Sources & evidence

ORD record
ord-0d0a5b31c9514733a7411d6de66267b3
Source dataset
Imidazopyridines dataset

Reaction notes

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