2-Amino-5-methylpyridine → HCID 178423205, compound

HRID 223960Notes

Reaction equation

HRID 223960 reaction equation
CC1=CC=C(N)N=C1.[C-]#[N+]C1CCCCC1.FC(F)(F)OC1=CC(Cl)=C(C=O)C(Cl)=C1>>CC1=CN2C(C=C1)=NC(=C2NC1CCCCC1)C1=C(Cl)C=C(OC(F)(F)F)C=C1Cl

Participants

6

Reactant 3

HCID 153482-Amino-5-methylpyridineHCID 79129Cyclohexyl isocyanideHCID 177507312,6-Dichloro-4-(trifluoromethoxy)benzaldehyde

Product 1

HCID 178423205HCID 178423205, compoundYield 48.54%

Reagents, catalysts & solvents 2

HCID 6422Trifluoroacetic acidCatalystHCID 3776IsopropanolSolvent2×

Conditions

Temperature
22 °C

Sources & evidence

ORD record
ord-4d01659ef29a484db1d3a56958587d8a
Source dataset
Imidazopyridines dataset

Reaction notes

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