2-Amino-5-methylpyridine → HCID 178423201, compound

HRID 224001Notes

Reaction equation

HRID 224001 reaction equation
CC1=CC=C(N)N=C1.[C-]#[N+]C1CCCCC1.OB(O)C1=CC=C(Cl)C(C=O)=C1F>>CC1=CN2C(C=C1)=NC(=C2NC1CCCCC1)C1=C(F)C(=CC=C1Cl)B(O)O

Participants

6

Reactant 3

HCID 153482-Amino-5-methylpyridineHCID 79129Cyclohexyl isocyanideHCID 57497262Boronic acid, B-(4-chloro-2-fluoro-3-formylphenyl)-

Product 1

HCID 178423201HCID 178423201, compoundYield 100%

Reagents, catalysts & solvents 2

HCID 6422Trifluoroacetic acidCatalystHCID 3776IsopropanolSolvent2×

Conditions

Temperature
22 °C

Sources & evidence

ORD record
ord-2c8b157b72604c949e71a25398c0665d
Source dataset
Imidazopyridines dataset

Reaction notes

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