Hydrochloric Acid → HCID 86610769, compound

HRID 2240084Notes

Reaction equation

HRID 2240084 reaction equation
[C:1]1([S:11]([CH2:14][C:15]2[CH:16]=[C:17]([CH:24]3OCC[O:25]3)[CH:18]=[CH:19][C:20]=2[N+:21]([O-:23])=[O:22])(=[O:13])=[O:12])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.Cl>C1COCC1>[C:1]1([S:11]([CH2:14][C:15]2[CH:16]=[C:17]([CH:18]=[CH:19][C:20]=2[N+:21]([O-:23])=[O:22])[CH:24]=[O:25])(=[O:12])=[O:13])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 68678121HCID 68678121, compound

Product 1

HCID 86610769HCID 86610769, compoundYield 95%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Conditions

Temperature
40 °C

Procedure

A mixture of 2-[3-(naphthalene-1-sulfonylmethyl)-4-nitro-phenyl]-[1,3]dioxolane (3.03 g, 7.6 mmoles), and 2N HCl (4 mL, 8 mmoles) in THF (30 mL) was stirred at 40° C. for 4 hours. The reaction mixture was cooled to room temperature, diluted with waster, extracted with EtOAc, dried over Na2SO4, and concentrated under vacuum to yield the title compound (2.56 g, 7.22 mmoles).

Workup

  1. temperatureThe reaction mixture was cooled to room temperature
  2. additiondiluted with waster
  3. extractionextracted with EtOAc
  4. dry with materialdried over Na2SO4
  5. concentrationconcentrated under vacuum

Sources & evidence

ORD record
ord-149d08cf41664a438d74eeb15e0382b6
Source dataset
uspto-grants-2010_05
Patent number
US07723329B2

Reaction notes

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