2-Amino-5-methylpyridine → HCID 178423172, compound

HRID 224109Notes

Reaction equation

HRID 224109 reaction equation
CC1=CC=C(N)N=C1.[C-]#[N+]C1CCCCC1.CC(C)(C)OC(=O)N1CCCC(C1)C=O>>CC1=CN2C(C=C1)=NC(C1CCCN(C1)C(=O)OC(C)(C)C)=C2NC1CCCCC1

Participants

6

Reactant 3

HCID 153482-Amino-5-methylpyridineHCID 79129Cyclohexyl isocyanideHCID 99644481-Boc-piperidine-3-carboxaldehyde

Product 1

HCID 178423172HCID 178423172, compoundYield 89.272%

Reagents, catalysts & solvents 2

HCID 6422Trifluoroacetic acidCatalystHCID 3776IsopropanolSolvent2×

Conditions

Temperature
22 °C

Sources & evidence

ORD record
ord-5d0f0d093729493fbdf720fab4453319
Source dataset
Imidazopyridines dataset

Reaction notes

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