Iodoethane → HCID 59128274, compound

HRID 2242996Notes

Reaction equation

HRID 2242996 reaction equation
[CH2:1](OC1C=C(C=CC=1C)C=O)[CH3:2].[Cl:13][C:14]1[C:21]([OH:22])=[CH:20][C:19]([OH:23])=[CH:18][C:15]=1[CH:16]=[O:17].I[CH2:25][CH3:26].C([O-])([O-])=O.[K+].[K+]>CN(C=O)C>[Cl:13][C:14]1[C:21]([O:22][CH2:1][CH3:2])=[CH:20][C:19]([O:23][CH2:25][CH3:26])=[CH:18][C:15]=1[CH:16]=[O:17]

Participants

6

Reactant 4

HCID 6340IodoethaneHCID 11430Potassium CarbonateHCID 252420583-Ethoxy-4-methylbenzaldehyde2×HCID 86607633HCID 86607633, compound

Product 1

HCID 59128274HCID 59128274, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

The title compound was prepared analogously to 3-ethoxy-4-methyl-benzaldehyde (intermediate D10, vide infra) by reaction of 2-chloro-3,5-dihydroxy benzaldehyde with iodoethane in DMF using K2CO3 as base. MS (ISP): 229.3 [M+H]+.

Sources & evidence

ORD record
ord-155896bc0dd749f9a2bda51919337fef
Source dataset
uspto-grants-2010_03
Patent number
US07674804B2

Reaction notes

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