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HRID2247403

反应详情

EQUATION

反应方程式

HRID 2247403 的结构方程式

REACTANTS

反应物

4
结构：CN(C)C=O
HCID6228

N,N-Dimethylformamide

C3H7NO

结构：C1COCCO1
HCID31275

1,4-Dioxane

C4H8O2

结构：CCc1cnc(CCN)o1
HCID11542801

未命名化合物

结构：Cc1nc(NC(N)=O)sc1-c1ccc(S(C)(=O)=O)c(F)c1
HCID57872135

未命名化合物

PRODUCTS

生成物

1
结构：CCc1cnc(CCNC(=O)Nc2nc(C)c(-c3ccc(S(C)(=O)=O)c(F)c3)s2)o1
HCID86598448

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCN(CC)CC
溶剂HCID8471

Triethylamine

C6H15N

PROCEDURE

实验过程

The title compound is prepared by the same procedure as -[5-(3-fluoro-4-methanesulfonyl-phenyl)-4-methyl-thiazol-2-yl]-urea (Example 177) by replacing ammonia (part 177b) with the hydrochloride salt of 2-(5-Ethyl-oxazol-2-yl)-ethylamine (details of preparation procedure follows below), by replacing dioxane with DMF and by using triethylamine as a base.