Hydracrylonitrile → HCID 86744987, compound

HRID 2248426Notes

Reaction equation

HRID 2248426 reaction equation
[C:1]([CH2:3][CH2:4][OH:5])#[N:2].[CH3:6][O:7][P:8](O)[OH:9].[Cl-].[CH:12]([N-:15][CH:16]([CH3:18])[CH3:17])([CH3:14])[CH3:13].C(N(C(C)C)CC)(C)C>C(Cl)Cl>[CH:12]([N-:15][CH:16]([CH3:18])[CH3:17])([CH3:14])[CH3:13].[C:1]([CH2:3][CH2:4][O:5][P:8]([OH:9])[O:7][CH3:6])#[N:2]

Participants

5

Reactant 3

HCID 8011HydracrylonitrileHCID 81531DiisopropylethylamineHCID 86744989HCID 86744989, compound

Product 1

HCID 86744987HCID 86744987, compoundYield 100.3%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

0.68 ml (10 mmol) of 2-cyanoethanol are reacted analogously to Example 2 with 2 ml (11 mmol) of phosphorous acid methyl ester-diisopropylamide-chloride in the presence of 8 ml of diisopropylethylamine in 20 ml of freshly distilled methylene chloride. Drying at 30° C. in a high vacuum gives 2.5 g of an oil which, according to 31P-NMR, contains 94% of the compound VIII. ##STR15##

Workup

  1. customDrying at 30° C. in a high vacuum

Sources & evidence

ORD record
ord-aa4b1e253b824303922ca62ef0b11ad1
Source dataset
uspto-grants-1991_08
Patent number
US05039796

Reaction notes

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