Methanol → HCID 14133519, compound

HRID 224960Notes

Reaction equation

HRID 224960 reaction equation
[CH3:1][O:2][C:3](=[O:6])[CH2:4]Br.[O-:7][C:8]#[N:9].[K+].[CH3:11][OH:12]>CN(C=O)C>[CH3:1][O:2][C:3](=[O:6])[CH2:4][NH:9][C:8]([O:12][CH3:11])=[O:7]

Participants

5

Reactant 3

HCID 887MethanolHCID 60984Methyl bromoacetateHCID 11378442Potassium cyanate

Product 1

HCID 14133519HCID 14133519, compoundYield 64.3%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

10.71 grams of monobromo acetic acid methyl ester, 8.52 grams of potassium cyanate and 7.85 grams of methanol were heated in 70 ml of DMF following the procedure of Example 1 gave 6.62 grams (64.3%) of methoxycarbonylamino acetic acid methyl ester having a boiling point of 67°-8° C./0.0013 mbar.

Sources & evidence

ORD record
ord-05549a776bd743fbaa64dcd7bca35360
Source dataset
uspto-grants-1980_11
Patent number
US04234744

Reaction notes

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