1,1'-Carbonyldiimidazole → HCID 54076766, compound

HRID 2251930Notes

Reaction equation

HRID 2251930 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH:7]=[CH:8][C:9]([OH:11])=O)[CH:2]=1.C1N=CN(C(N2C=NC=C2)=O)C=1.[CH:24]([NH:37][CH2:38][CH2:39][CH2:40][CH2:41][NH2:42])([C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1)[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>C1COCC1>[CH:24]([NH:37][CH2:38][CH2:39][CH2:40][CH2:41][NH:42][C:9](=[O:11])[CH:8]=[CH:7][C:3]1[CH:2]=[N:1][CH:6]=[CH:5][CH:4]=1)([C:31]1[CH:32]=[CH:33][CH:34]=[CH:35][CH:36]=1)[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1

Participants

5

Reactant 3

HCID 682631,1'-CarbonyldiimidazoleHCID 1019843-(3-Pyridinyl)-2-propenoic acidHCID 124911934-(Benzhydryl-amino)-butylamine

Product 1

HCID 54076766HCID 54076766, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Batch size: 1.9 g (12.6 mmol) 3-(3-pyridyl)-acrylic acid, 2.5 g (15.1 mmol) CDI and 3.7 g (14.5 mmol) 4-(benzhydryl-amino)-butylamine in 60 ml abs. THF.

Sources & evidence

ORD record
ord-d8e07e6e8d9e457f89bc7a52a3604aa4
Source dataset
uspto-grants-2008_01
Patent number
US07320993B1

Reaction notes

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