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HRID2261397

反应详情

EQUATION

反应方程式

HRID 2261397 的结构方程式

REACTANTS

反应物

2
结构：[Li+].[OH-]
HCID3939

Lithium hydroxide anhydrous

HLiO

结构：COC(=O)CCC1=CCCN(Cc2ccc(NC(C)=O)cc2)C1=O
HCID57443428

未命名化合物

PRODUCTS

生成物

1
结构：CC(=O)Nc1ccc(CN2CCC=C(CCC(=O)O)C2=O)cc1
HCID11151229

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：C1CCOC1
溶剂HCID8028

Tetrahydrofuran

C4H8O

PROCEDURE

实验过程

3-[1-(4-acetylamino-benzyl)-2-oxo-1,2,5,6-tetrahydro-pyridin-3-yl]-propionic acid methyl ester (i) prepared by above Step 2 of Example 18 dissolved in organic solvent such as tetrahydrofurane was reacted with LiOH to give 3-[1-(4-acetylamino-benzyl)-2-oxo-1,2,5,6-tetrahydro-pyridin-3-yl]-propionic acid (k).