HCID 59595974, compound → HCID 59595979, compound

HRID 2264182Notes

Reaction equation

HRID 2264182 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([C:17]2[CH:22]=[CH:21][N:20]=[CH:19][CH:18]=2)[C:7]([C:11]2[CH:16]=[CH:15][N:14]=[CH:13][CH:12]=2)=[N:8][C:9]=1[NH2:10])([O-])=O>C(O)C.Cl.[Fe]>[N:14]1[CH:15]=[CH:16][C:11]([C:7]2[C:6]([C:17]3[CH:22]=[CH:21][N:20]=[CH:19][CH:18]=3)=[CH:5][C:4]([NH2:1])=[C:9]([NH2:10])[N:8]=2)=[CH:12][CH:13]=1

Participants

5

Reactant 1

HCID 59595974HCID 59595974, compound

Product 1

HCID 59595979HCID 59595979, compoundYield 93%

Reagents, catalysts & solvents 3

HCID 23925IronCatalystHCID 313Hydrochloric AcidSolventHCID 702EthanolSolvent

Conditions

Temperature
90 °C

Procedure

To a solution of 5′-nitro-4,2′:3′,4″-terpyridin-6′-amine (0.144 g, 0.490 mmol) in ethanol (5 mL), 0.300 mL of hydrogen chloride and 0.140 g (2.45 mmol) of iron were added. The mixture was heated at 90° C. for 2 h and the solvent was evaporated. The crude mixture was extracted between ethyl acetate and water. The organic layer was dried (MgSO4) and the solvent evaporated to give the title compound (0.120 g, 93% of yield).

Workup

  1. customthe solvent was evaporated
  2. extractionThe crude mixture was extracted between ethyl acetate and water
  3. dry with materialThe organic layer was dried (MgSO4)
  4. customthe solvent evaporated

Sources & evidence

ORD record
ord-4d4759be3b444662892b08f3ee5cb429
Source dataset
uspto-grants-2010_12
Patent number
US07855202B2

Reaction notes

Loading…