2-Bromopropane → HCID 15675195, compound

HRID 2264472Notes

Reaction equation

HRID 2264472 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[OH:10])[CH:5]=[O:6].Br[CH:12]([CH3:14])[CH3:13].C([O-])([O-])=O.[K+].[K+].C(O[C:24]1[CH:25]=C(C=C[C:31]=1C)C=O)C>CN(C=O)C>[CH:12]([O:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[O:10][CH:24]([CH3:25])[CH3:31])[CH:5]=[O:6])([CH3:14])[CH3:13]

Participants

6

Reactant 4

HCID 63582-BromopropaneHCID 87683,4-DihydroxybenzaldehydeHCID 11430Potassium CarbonateHCID 252420583-Ethoxy-4-methylbenzaldehyde2×

Product 1

HCID 15675195HCID 15675195, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

The title compound was prepared by reaction of 3,4-dihydroxybenzaldehyde with 2-bromopropane in DMF using K2CO3 as base in analogy to the preparation of 3-ethoxy-4-methyl-benzaldehyde (intermediate D2).

Sources & evidence

ORD record
ord-87cb0b30a5734a839d0932d0405bd17b
Source dataset
uspto-grants-2010_12
Patent number
US07855194B2

Reaction notes

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