Potassium Bromide → HCID 178433127, compound

HRID 2268824Notes

Reaction equation

HRID 2268824 reaction equation
C[C:2]1[C:23](C)=[CH:22][C:5]2[N:6]=[C:7]([NH:9][C:10]3[N:15]=[C:14]([OH:16])[C:13]([CH2:17][C:18]([OH:20])=[O:19])=[C:12]([CH3:21])[N:11]=3)[NH:8][C:4]=2[CH:3]=1.[K+].[Br-]>CN(C=O)C>[N:6]1[C:5]2[CH:22]=[CH:23][CH:2]=[CH:3][C:4]=2[NH:8][C:7]=1[NH:9][C:10]1[N:15]=[C:14]([OH:16])[C:13]([CH2:17][C:18]([OH:20])=[O:19])=[C:12]([CH3:21])[N:11]=1

Participants

4

Reactant 2

HCID 253877Potassium BromideHCID 178422319HCID 178422319, compound

Product 1

HCID 178433127HCID 178433127, compoundYield 5%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

was prepared according to procedure used for (2) in Example 1; yield 5%. mp: >300° C. (DMF). IR (KBr): υ=2878, 1748. 1700, 1625, 1557, 1474, 1357, 1219, 744 cm−1. 1H-NMR (CF3CO2D): δ=2.64 (s, 3H, CH3), 3.88 (s, 2H, CH2), 7.52 (m, 2H, 2×Harom), 7.67 (m, 2H, 2×Harom). Accurate mass: calculated: 299.1018. Found 299.1013. Analysis calculated for C14H13N5O3: C, 55.2; H, 4.40; N, 23.40. Found: C. 55.4; H, 4.7; N, 22.5.

Workup

  1. customwas prepared

Sources & evidence

ORD record
ord-e5ce012435cd4cdda604069def227998
Source dataset
uspto-grants-2001_12
Patent number
US06329383B1

Reaction notes

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