Ethanol →

HRID 2271270Notes

Reaction equation

HRID 2271270 reaction equation
[CH2:1]([OH:3])[CH3:2].[Mg:4].[C:5]([O:13]CC)(=[O:12])[CH2:6][C:7]([O:9]CC)=[O:8]>C(Cl)(Cl)(Cl)Cl.C1(C)C=CC=CC=1>[CH2:1]([CH:6]([C:7]([O-:9])=[O:8])[C:5]([O-:13])=[O:12])[CH3:2].[CH2:1]([O:3][Mg+2:4])[CH3:2]

Participants

5

Reactant 3

HCID 702Ethanol2×HCID 7761Diethyl MalonateHCID 5462224Magnesium

Product 0

No Product data yet.

Reagents, catalysts & solvents 2

HCID 5943Carbon TetrachlorideCatalystHCID 1140TolueneSolvent

Conditions

Temperature
60 °C

Procedure

Separately, 0.9 ml of absolute ethanol and two drops of carbon tetrachloride were added to 0.4 g of metallic magnesium. When a reaction began, a mixture of 2.6 ml of diethyl malonate, 1.6 ml of absolute ethanol and 6 ml of toluene was added dropwise to the reaction mixture at a temperature not higher than 60° C., followed by stirring at 60° C. for 1 hour to give ethoxymagnesium ethyl malonate.

Workup

  1. additionwas added dropwise to the reaction mixture at a temperature not higher than 60° C.

Sources & evidence

ORD record
ord-8b1556e51b3c45ada3a4335d56bd4788
Source dataset
uspto-grants-2001_12
Patent number
US06333431B1

Reaction notes

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