反应详情

温度

60 °C

A mixture of tert-butyl (2-(benzyloxy)-5-(methoxymethoxy)pyridin-4-yl)carbamate (11.0 g) in THF (10 mL) and 6 M hydrochloric acid (30 mL) was stirred at 60° C. for 8 hr. The reaction mixture was cooled to 0° C., and the precipitate was collected by filtration, and washed with hexane. The obtained solid was dried under reduced pressure to give the title compound (5.87 g).

1. temperatureThe reaction mixture was cooled to 0° C.
2. filtrationthe precipitate was collected by filtration
3. washwashed with hexane
4. customThe obtained solid was dried under reduced pressure