Hydrochloric Acid → HCID 23459451, compound

HRID 2287122Notes

Reaction equation

HRID 2287122 reaction equation
[C:1]1([C:7]2([CH2:13][CH2:14]OS(C)(=O)=O)[CH:12]=[CH:11][CH2:10][CH:9]=[CH:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:20][NH2:21].[ClH:22]>>[ClH:22].[CH3:20][NH:21][CH2:14][CH2:13][C:7]1([C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)[CH:12]=[CH:11][CH2:10][CH:9]=[CH:8]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 6329MethylamineHCID 21764419HCID 21764419, compound

Product 1

HCID 23459451HCID 23459451, compound

Procedure

Methanesulfonic acid 2-(1-phenyl-2,5-cyclohexadien-1-yl)-ethyl ester is reacted with methylamine by an analogous procedure to that described in Example 7. The crude product obtained is converted in the usual manner into the hydrochloride which is recrystallized from isopropanol. There is obtained N-methyl-1-phenyl-2,5-cyclohexadien-1-ethylamine hydrochloride having a melting point of 172°-173° C.

Workup

  1. customThe crude product obtained
  2. customis recrystallized from isopropanol

Sources & evidence

ORD record
ord-be0fa4d3b078439ea4d1dacfa37a7edd
Source dataset
uspto-grants-1981_05
Patent number
US04269788

Reaction notes

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