Phthalimide → HCID 86737753, compound

HRID 2287217Notes

Reaction equation

HRID 2287217 reaction equation
[Cl:1][C:2]1[CH:21]=[C:20]([C:22]([O:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH3:36])=[O:23])[CH:19]=[CH:18][C:3]=1[NH:4][C:5](=[O:17])[CH:6]([C:8](=[O:16])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[CH3:15])Br.[C:37]1(=[O:47])[NH:41][C:40](=[O:42])[C:39]2=[CH:43][CH:44]=[CH:45][CH:46]=[C:38]12.C(N(CC)CC)C>CN(C)C=O>[Cl:1][C:2]1[CH:21]=[C:20]([C:22]([O:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH3:36])=[O:23])[CH:19]=[CH:18][C:3]=1[NH:4][C:5](=[O:17])[CH:6]([C:8](=[O:16])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[CH3:15])[N:41]1[C:40](=[O:42])[C:39]2=[CH:43][CH:44]=[CH:45][CH:46]=[C:38]2[C:37]1=[O:47]

Participants

5

Reactant 3

HCID 6809PhthalimideHCID 8471TriethylamineHCID 86737754HCID 86737754, compound

Product 1

HCID 86737753HCID 86737753, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

29 g of 2'-chloro-4'-dodecyloxycarbonyl-2-methyl-α-bromo-benzoylacetanilide, 29 g of phthalimide and 20 g of triethylamine were stirred for 3 hours at room temperature in 200 ml of dimethylformamide. The reaction mixture was processed in a manner similar to Synthesis example 1 except for using ligroin for recrystallization to obtain 20 g of coupler 9 having a melting point of from 100° to 101° C.

Workup

  1. customThe reaction mixture was processed in a manner similar to Synthesis example 1 except
  2. customfor recrystallization
  3. customto obtain 20 g of coupler 9 having a melting point of from 100° to 101° C.

Sources & evidence

ORD record
ord-0876bf94464947acbe4f96992763689c
Source dataset
uspto-grants-1981_05
Patent number
US04269936

Reaction notes

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