Hydrochloric Acid → HCID 18697997, compound

HRID 2289542Notes

Reaction equation

HRID 2289542 reaction equation
Cl.[Cl:2][C:3]1[CH:8]=[CH:7][C:6]([S:9]([N:12]2[CH2:17][CH2:16][CH:15]([C:18]([N:20]3[CH2:25][CH2:24][N:23](C(OOC(C)(C)C)=O)[CH2:22][CH2:21]3)=[O:19])[CH2:14][CH2:13]2)(=[O:11])=[O:10])=[CH:5][CH:4]=1>C(OCC)(=O)C>[ClH:2].[Cl:2][C:3]1[CH:8]=[CH:7][C:6]([S:9]([N:12]2[CH2:13][CH2:14][CH:15]([C:18]([N:20]3[CH2:21][CH2:22][NH:23][CH2:24][CH2:25]3)=[O:19])[CH2:16][CH2:17]2)(=[O:11])=[O:10])=[CH:5][CH:4]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 18698059HCID 18698059, compound

Product 1

HCID 18697997HCID 18697997, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent2×

Procedure

Ethyl acetate saturated with gaseous HCl was added to a solution of 1-(4-chlorophenylsulphonyl)-4-[1-(t-butoxyoxycarbonyl)piperazine-4-ylcarbonyl]piperidine (1.10 g) in ethyl acetate (25 ml). The reaction was stirred at room temperature for 2 hours. Solvent was removed by evaporation to give the crude 1-(4-chlorophenylsulphonyl)-4-(4-piperazinylcarbonyl)piperidine hydrochloride.

Workup

  1. customSolvent was removed by evaporation

Sources & evidence

ORD record
ord-0e12433721ea452abd7894ba12a986de
Source dataset
uspto-grants-2000_07
Patent number
US06093718

Reaction notes

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