Propylamine → HCID 43721984, compound

HRID 2290607Notes

Reaction equation

HRID 2290607 reaction equation
Cl[C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([O:8][CH3:9])[N:3]=1.[CH2:10]([NH2:13])[CH2:11][CH3:12]>O>[CH3:9][O:8][C:4]1[C:5]([NH:13][CH2:10][CH2:11][CH3:12])=[CH:6][CH:7]=[CH:2][N:3]=1

Participants

4

Reactant 2

HCID 7852PropylamineHCID 870092-Chloro-6-methoxypyridine

Product 1

HCID 43721984HCID 43721984, compoundYield 40.2%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

In the same reacting apparatus as in Example 1, 20 g of 2-chloro-6-methoxypyridine, 25 g of n-propylamine and 80 ml of water were charged and they were subjected to reacting each other at 180° C. for 5 hours. After completion of the reaction, the similar experimental procedure was carried out to give 9.3 g of 2-methoxy-n-propylaminopyridine of b.p. 90°-91° C./4 mmHg.

Workup

  1. additionwere charged
  2. customother at 180° C.
  3. customfor 5 hours
  4. customAfter completion of the reaction

Sources & evidence

ORD record
ord-f87c938b6af440639f9e256aa717beac
Source dataset
uspto-grants-1986_10
Patent number
US04617397

Reaction notes

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