Carbon Disulfide → HCID 86741089, compound

HRID 2291005Notes

Reaction equation

HRID 2291005 reaction equation
[OH:1][CH2:2][CH2:3][N:4]1[CH2:9][CH2:8][O:7][CH2:6][CH2:5]1.O1CCCC1.[H-].[Na+:16].[C:17](=[S:19])=[S:18]>>[O:1]([CH2:2][CH2:3][N:4]1[CH2:9][CH2:8][O:7][CH2:6][CH2:5]1)[C:17]([S-:19])=[S:18].[Na+:16]

Participants

5

Reactant 4

HCID 6348Carbon DisulfideHCID 8028TetrahydrofuranHCID 24758Sodium hydrideHCID 611632-Morpholinoethanol

Product 1

HCID 86741089HCID 86741089, compound

Procedure

To a stirred solution of 4.91 g. of N-(2-hydroxyethyl)morpholine in 250 ml. of anhydrous tetrahydrofuran at room temperature was added 1.79 g. of a 50% dispersion of sodium hydride in mineral oil. A precipitate formed. The mixture was stirred for 30 minutes, and then 2.75 ml. of carbon disulfide was added, causing the initial precipitate to dissolve. The reaction mixture was stirred for 30 minutes during which time a further precipitate formed. To the mixture was added 200 ml. of anhydrous ether, and the precipitate was recovered by filtration. The solid was washed with ether, and dried, to give 8.8 g. of the title compound.

Workup

  1. customA precipitate formed
  2. dissolutionto dissolve
  3. stirringThe reaction mixture was stirred for 30 minutes during which time a further precipitate
  4. customformed
  5. additionTo the mixture was added 200 ml
  6. filtrationof anhydrous ether, and the precipitate was recovered by filtration
  7. washThe solid was washed with ether
  8. customdried
  9. customto give 8.8 g

Sources & evidence

ORD record
ord-15f8e9c13f0e497c8dd61bbe18234dfc
Source dataset
uspto-grants-1986_10
Patent number
US04619783

Reaction notes

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