Triethylamine → HCID 14648884, compound

HRID 2291393Notes

Reaction equation

HRID 2291393 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:11]2([C:17]#[N:18])[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12]2)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10].[ClH:19].[CH3:20][CH:21]([NH:23][CH2:24][CH2:25][CH2:26][CH2:27][C:28]1[CH:33]=[CH:32][C:31]([O:34][CH3:35])=[C:30]([O:36][CH3:37])[CH:29]=1)[CH3:22].C(N(CC)CC)C.C([BH3-])#N.[Na+]>C(O)C>[ClH:19].[CH3:37][O:36][C:30]1[CH:29]=[C:28]([CH2:27][CH2:26][CH2:25][CH2:24][N:23]([CH:21]([CH3:22])[CH3:20])[CH:14]2[CH2:13][CH2:12][C:11]([C:17]#[N:18])([C:5]3[CH:6]=[CH:7][C:8]([O:9][CH3:10])=[C:3]([O:2][CH3:1])[CH:4]=3)[CH2:16][CH2:15]2)[CH:33]=[CH:32][C:31]=1[O:34][CH3:35]

Participants

6

Reactant 4

HCID 8471TriethylamineHCID 46393531-(3,4-Dimethoxyphenyl)cyclohexanecarbonitrileHCID 5003444Sodium cyanoborohydrideHCID 14648882HCID 14648882, compound

Product 1

HCID 14648884HCID 14648884, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of 4-(3,4-dimethoxyphenyl)-4-cyanocyclohexane (5 mmol), N-(1-methylethyl)-4-(3,4-dimethoxyphenyl) butylamine hydrochloride (5 mmol), triethylamine (6 mmol) and sodium cyanoborohydride (6 mmol) in 25 ml ethanol was stirred at 25° C. for 72 hours and worked up and recrystallized. ##STR8##

Workup

  1. customrecrystallized

Sources & evidence

ORD record
ord-a2d0f402b9104a2da40b7fa9e91e658f
Source dataset
uspto-grants-1989_01
Patent number
US04795757

Reaction notes

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