HRID2292050

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6422

未命名化合物

结构：CC(=O)OCC1=C(C(=O)OC(c2ccccc2)c2ccccc2)N2C(=O)[C@@H](Nc3nc(-c4ccccc4)cs3)[C@H]2SC1

HCID14349724

未命名化合物

PRODUCTS

生成物

结构：CC(=O)OCC1=C(C(=O)O)N2C(=O)[C@@H](Nc3nc(-c4ccccc4)cs3)[C@H]2SC1

HCID14349728

未命名化合物

收率 70%

AUXILIARIES

试剂、催化剂与溶剂

催化剂HCID7519

Anisole

C7H8O

溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

A mixture of 182 mg of (6R-trans)-3-[(acetyloxy)methyl]-8-oxo-7-[(4-phenyl-2-thiazolyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, diphenylmethyl ester, 0.5 ml of trifluoroacetic acid, 3 drops of anisole and 3 ml of dichloromethane was reacted as described in Example 2, giving 92 mg of the desired compound.

WORKUP

后处理

customwas reacted