1-Bromo-3-methylbutane → HCID 21472394, compound

HRID 2294966Notes

Reaction equation

C(OC1C=[CH:9][C:8]([C:11]#N)=[CH:7][CH:6]=1)C=C.[I:13][C:14]1[CH:19]=[CH:18][C:17]([OH:20])=[CH:16][CH:15]=1.C(Br)CC(C)C.C(=O)([O-])[O-:28].[K+].[K+]>>[I:13][C:14]1[CH:19]=[CH:18][C:17]([OH:20])=[C:16]([O:28][CH2:6][CH2:7][CH:8]([CH3:11])[CH3:9])[CH:15]=1

Participants

Reactant 4

HCID 78911-Bromo-3-methylbutane

HCID 108944-Iodophenol

HCID 11430Potassium Carbonate

HCID 2579494-(ALLYLOXY)BENZONITRILE

Product 1

HCID 21472394HCID 21472394, compound

Procedure

Using the method described in Example 48 for the preparation of 4-cyanophenol allyl ether, 4-iodophenol was reacted with isoamylbromide in the presence of potassium carbonate to give 4-iodo-isoamyloxyphenol as an oil, NMR(CDCl3): 0.95(6H,d), 1.66(2H,q), 1.68-1.92(1H,m), 3.93(2H,t), 6.63-6.72(2H,d), 7.49-7.59(2H,d); m/z290(M).

Sources & evidence

ORD record: ord-9c394f6504b0487dbbe520f3b465ab12
Source dataset: uspto-grants-1997_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05691349

Reaction notes

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