Tetraethylene Glycol → HCID 18374579, compound

HRID 2300707Notes

Reaction equation

HRID 2300707 reaction equation
[Na].[CH2:2]([OH:14])[CH2:3][O:4][CH2:5][CH2:6][O:7][CH2:8][CH2:9][O:10][CH2:11][CH2:12][OH:13].[C:15]([O:19][C:20]([CH3:23])([CH3:22])[CH3:21])(=[O:18])[CH:16]=[CH2:17].[Cl-].[NH4+]>O1CCCC1>[C:20]([O:19][C:15]([CH2:16][CH2:17][O:13][CH2:12][CH2:11][O:10][CH2:9][CH2:8][O:7][CH2:6][CH2:5][O:4][CH2:3][CH2:2][O:14][CH2:17][CH2:16][C:15]([O:19][C:20]([CH3:23])([CH3:22])[CH3:21])=[O:18])=[O:18])([CH3:23])([CH3:22])[CH3:21]

Participants

6

Reactant 4

HCID 8200Tetraethylene GlycolHCID 15458tert-Butyl acrylateHCID 25517Ammonium ChlorideHCID 5360545Sodium2×

Product 1

HCID 18374579HCID 18374579, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

0.4 g of sodium is added to a solution of 91 g of tetraethylene glycol in 250 ml of tetrahydrofuran, and the mixture is stirred at room temperature. Once the sodium has dissolved, 145 ml of tert-butyl acrylate are added. The mixture is stirred for 12 h. The reaction solution is neutralized with ammonium chloride, concentrated, taken up in aqueous sodium chloride solution and extracted with ethyl acetate. The organic phase is concentrated. The residue is 39.

Workup

  1. stirringThe mixture is stirred for 12 h
  2. concentrationconcentrated
  3. extractionextracted with ethyl acetate
  4. concentrationThe organic phase is concentrated

Sources & evidence

ORD record
ord-582fe973b5b2440db0306c3105b9103d
Source dataset
uspto-grants-2002_12
Patent number
US06498156B2

Reaction notes

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