反应详情

温度

5 °C

0.85 g of 5-amino-N-tert.-butyl-2-dimethylaminocarbonyl-benzenesulfonamide (Example e) is dissolved in 3.5 ml of DMF at 0° C., and 0.28 g of propionyl chloride and 0.50 ml of triethylamine are added. After the mixture has been stirred at 5° C. for 1 hour, it is taken up in ethyl acetate and washed successively with dilute hydrochloric acid and water. After the mixture has been dried over MgSO4 and the organic phase has been concentrated, 0.60 g of a highly viscous substance, which is employed in subsequent reactions without further purification (Example k), is obtained.

1. washwashed successively with dilute hydrochloric acid and water
2. dry with materialAfter the mixture has been dried over MgSO4
3. concentrationthe organic phase has been concentrated
4. custom0.60 g of a highly viscous substance, which is employed in subsequent reactions without further purification (Example k)
5. customis obtained