Triethylamine → HCID 54395400, compound

HRID 2301559Notes

Reaction equation

HRID 2301559 reaction equation
[Cl:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=[C:4]([Cl:11])[C:3]=1[S:12](Cl)(=[O:14])=[O:13].[NH2:16][CH2:17][CH2:18][N:19]1[CH2:24][CH2:23][O:22][CH2:21][CH2:20]1.C(N(CC)CC)C>>[N:19]1([CH2:18][CH2:17][NH:16][S:12]([C:3]2[C:4]([Cl:11])=[CH:5][CH:6]=[C:7]([N+:8]([O-:10])=[O:9])[C:2]=2[Cl:1])(=[O:14])=[O:13])[CH2:24][CH2:23][O:22][CH2:21][CH2:20]1

Participants

4

Reactant 3

HCID 8471TriethylamineHCID 4082852-MorpholinoethylamineHCID 234477722,6-Dichloro-3-nitrobenzene-1-sulfonyl chloride

Product 1

HCID 54395400HCID 54395400, compoundYield 75%

Procedure

Following the general procedure for sulfonamide formation outlined in example 15, 2,6-dichloro-3-nitrobenzenesulfonyl chloride (600 mg, 2.07 mmol), 4-(2-aminoethyl) morpholine (269 mg, 2.07 mmol) and triethylamine (0.58mL, 4.13 mmol) were reacted to form the desired product (593 mg, 75%). LC-MS (m/z) 384.0 (M+).

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-ad86de335f724b03966fb9a48fb01887
Source dataset
uspto-grants-2002_12
Patent number
US06500863B1

Reaction notes

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