Tert-Butylamine → HCID 17927834, compound

HRID 2301643Notes

Reaction equation

HRID 2301643 reaction equation
[Cl:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=[C:4]([Cl:11])[C:3]=1[S:12](Cl)(=[O:14])=[O:13].[C:16]([NH2:20])([CH3:19])([CH3:18])[CH3:17].C(N(CC)CC)C>>[C:16]([NH:20][S:12]([C:3]1[C:4]([Cl:11])=[CH:5][CH:6]=[C:7]([N+:8]([O-:10])=[O:9])[C:2]=1[Cl:1])(=[O:14])=[O:13])([CH3:19])([CH3:18])[CH3:17]

Participants

4

Reactant 3

HCID 6385Tert-ButylamineHCID 8471TriethylamineHCID 234477722,6-Dichloro-3-nitrobenzene-1-sulfonyl chloride

Product 1

HCID 17927834HCID 17927834, compoundYield 75%

Procedure

Following the general procedure for sulfonamide formation outlined in example 15, 2,6-dichloro-3-nitrobenzenesulfonyl chloride (2.0 g, 6.88 mmol), tert-butylamine (503 mg, 6.88mmol) and triethylamine(l.43 mL, 10.32 mmol) were reacted to form the desired product (1.67 g, 75%). 1H NMR (MeOD-d4): δ 7.91 (d, 1H), 7.78 (d, 1H), 1.25 (s, 9H).

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-30d41e327aab4db4a99b7e1c1da1b2f2
Source dataset
uspto-grants-2002_12
Patent number
US06500863B1

Reaction notes

Loading…