Hydrochloric Acid → HCID 18433615, compound

HRID 2306201Notes

Reaction equation

HRID 2306201 reaction equation
C(OC([NH:8][C:9]1[C:18]2[C:13](=[CH:14][CH:15]=[C:16]([O:19][Si:20]([C:23]([CH3:26])([CH3:25])[CH3:24])([CH3:22])[CH3:21])[CH:17]=2)[CH:12]=[CH:11][CH:10]=1)=O)(C)(C)C.CCOCC.[ClH:32]>CCOC(C)=O>[ClH:32].[NH2:8][C:9]1[C:18]2[C:13](=[CH:14][CH:15]=[C:16]([O:19][Si:20]([C:23]([CH3:26])([CH3:25])[CH3:24])([CH3:21])[CH3:22])[CH:17]=2)[CH:12]=[CH:11][CH:10]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 18433594HCID 18433594, compound

Product 1

HCID 18433615HCID 18433615, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

A solution of 1-(tert-butoxycarbonylamino)-7-(tert-butyldimethylsilyloxy)naphthalene, as described above in Step B, (5.00 g, 13.4 mmol) in EtOAc (240 mL) and Et2O (60 mL) at ambient temperature was saturated with HCl (g). After 1 hour, the mixture was concentrated in vacuo to yield the desired product as a pale solid.

Workup

  1. customat ambient temperature
  2. concentrationthe mixture was concentrated in vacuo

Sources & evidence

ORD record
ord-b9125213566a4c12a1d49dde9af3ebce
Source dataset
uspto-grants-2002_08
Patent number
US06441017B1

Reaction notes

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