Benzyl Bromide → HCID 12045651, compound

HRID 2309753Notes

Reaction equation

HRID 2309753 reaction equation
Cl.[CH2:2]([O:9][NH2:10])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[CH2:11](Br)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1.C(=O)([O-])[O-].[Na+].[Na+]>CN(C)C=O>[CH2:11]([N:10]([CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1)[O:9][CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

Participants

5

Reactant 3

HCID 7498Benzyl BromideHCID 10340Sodium CarbonateHCID 102312Benzyloxyamine hydrochloride

Product 1

HCID 12045651HCID 12045651, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A mixture of 13.04 g of benzyloxyaminehydrochloride, 20.0 ml of benzylbromide, and 32.0 g of sodium carbonate in 85 ml of dimethylformamide is stirred at room temperature for four days. The reaction mixture is worked up as in Example I and the crude product is distilled under reduced pressure to afford the title compound as a clear colorless liquid.

Workup

  1. distillationthe crude product is distilled under reduced pressure

Sources & evidence

ORD record
ord-86200743de9c4ea9ad5893948d7e1639
Source dataset
uspto-grants-1987_09
Patent number
US04696964

Reaction notes

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