Tetrahydrofuran → HCID 178427350, compound

HRID 2310442Notes

Reaction equation

HRID 2310442 reaction equation
[CH2:66]1[O:67][CH2:68][CH2:69][CH2:70]1.[CH3:71][CH2:72][O:73][C:74](=[O:75])[CH3:76].[CH:57]([N:58]([CH:59]([CH3:60])[CH3:61])[CH2:62][CH3:63])([CH3:64])[CH3:65].[NH2:41][CH:42]([CH3:43])[CH:44]1[CH2:45][CH2:46][N:47]([C:50](=[O:51])[O:52][C:53]([CH3:54])([CH3:55])[CH3:56])[CH2:48][CH2:49]1.[P:1]([O:2][CH2:3][CH3:35])([O:36][CH2:37][CH3:38])([O:39][c:4]1[n:5][cH:6][c:7]([C:33]#[N:34])[c:8](-[c:10]2[cH:11][n:12]([S:23](=[O:24])(=[O:25])[c:26]3[cH:27][cH:28][c:29]([CH3:30])[cH:31][cH:32]3)[c:13]3[n:14][cH:15][c:16]([C:19]([F:20])([F:21])[F:22])[cH:17][c:18]23)[n:9]1)=[O:40]>>[c:4]1([NH:41][CH:42]([CH3:43])[CH:44]2[CH2:45][CH2:46][N:47]([C:50](=[O:51])[O:52][C:53]([CH3:54])([CH3:55])[CH3:56])[CH2:48][CH2:49]2)[n:5][cH:6][c:7]([C:33]#[N:34])[c:8](-[c:10]2[cH:11][n:12]([S:23](=[O:24])(=[O:25])[c:26]3[cH:27][cH:28][c:29]([CH3:30])[cH:31][cH:32]3)[c:13]3[n:14][cH:15][c:16]([C:19]([F:20])([F:21])[F:22])[cH:17][c:18]23)[n:9]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 81531DiisopropylethylamineHCID 22647295tert-Butyl 4-(1-aminoethyl)piperidine-1-carboxylateHCID 594143445-cyano-4-(1-tosyl-5-(trifluoromethyl)-1H-pyrrolo [2,3-b]pyridin-3-yl)pyrimidin-2-yl diethyl phosphate

Product 1

HCID 178427350HCID 178427350, compound

Sources & evidence

ORD record
ord-8861dd224ef54d9db43c830c6cffed39
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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