Triethylamine → Cyclopropyl-ethyl-(2-methyl-4-trimethylsilanylethynyl-benzyl)-amine

HRID 2311858Notes

Reaction equation

[Br:1][c:2]1[cH:3][c:4]([CH3:15])[c:5]([CH2:6][N:7]([CH2:8][CH3:9])[CH:10]2[CH2:11][CH2:12]2)[cH:13][cH:14]1.[CH3:16][Si:17]([CH3:18])([CH3:19])[C:20]#[CH:21].[CH3:22][CH2:23][N:24]([CH2:25][CH3:26])[CH2:27][CH3:28].[Cu:29][I:30]>>[c:2]1([C:21]#[C:20][Si:17]([CH3:16])([CH3:18])[CH3:19])[cH:3][c:4]([CH3:15])[c:5]([CH2:6][N:7]([CH2:8][CH3:9])[CH:10]2[CH2:11][CH2:12]2)[cH:13][cH:14]1

Participants

Reactant 4

HCID 8471Triethylamine

HCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)

HCID 66111Trimethylsilylacetylene

HCID 22568961(4-Bromo-2-methyl-benzyl)-cyclopropyl-ethyl-amine

Product 1

HCID 22568965Cyclopropyl-ethyl-(2-methyl-4-trimethylsilanylethynyl-benzyl)-amine

Sources & evidence

ORD record: ord-5348e7e6f4514245b0b22869d9e903e1
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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