Chloride → 8-Bromo-5,6-difluorochroman-4-one
Reaction equation
[Al+3:28].[Br:7][c:8]1[c:9]([O:10][CH2:11][CH2:12][C:13](=[O:14])[OH:15])[cH:16][c:17]([F:21])[c:18]([F:20])[cH:19]1.[Cl-:27].[Cl-:29].[Cl-:30].[Cl:1][C:2]([C:3]([Cl:4])=[O:5])=[O:6].[Cl:31][CH2:32][Cl:33].[O:22]=[CH:23][N:24]([CH3:25])[CH3:26]>>[Br:7][c:8]1[c:9]2[c:16]([c:17]([F:21])[c:18]([F:20])[cH:19]1)[C:13](=[O:15])[CH2:12][CH2:11][O:10]2Participants
7
Sources & evidence
- ORD record
- ord-b4a8977e4e3e43baa0dc6fd26b4752d6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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