Hydrochloric Acid → 4-benzyl-7-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-3,4-dihydropyrido[2,3-b]pyrazin-2(1H)-one
Reaction equation
[C:22]([CH2:23][P+:24]([CH3:25])([CH3:26])[CH3:27])#[N:28].[C:52](#[N:53])[CH2:54][CH3:55].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[c:9]2[c:10]([cH:15][c:16]([CH2:19][OH:20])[cH:17][n:18]2)[NH:11][C:12](=[O:14])[CH2:13]1.[CH2:29]([N:30]([CH:31]([CH3:32])[CH3:33])[CH:34]([CH3:35])[CH3:36])[CH3:37].[Cl:39][c:40]1[cH:41][cH:42][c:43]([N:46]2[CH2:47][CH2:48][NH:49][CH2:50][CH2:51]2)[cH:44][cH:45]1.[ClH:38].[I-:21].[OH2:56]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[c:9]2[c:10]([cH:15][c:16]([CH2:19][N:49]3[CH2:48][CH2:47][N:46]([c:43]4[cH:42][cH:41][c:40]([Cl:39])[cH:45][cH:44]4)[CH2:51][CH2:50]3)[cH:17][n:18]2)[NH:11][C:12](=[O:14])[CH2:13]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-2870350361ce4cef8feaf46fbbbffb1b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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