Hydrochloric Acid → (5-(2-Chlorobenzoyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)(9-(pyridin-4-yl)-3,9-diazaspiro[5.5]undecan-3-yl)methanone

HRID 2316101Notes

Reaction equation

HRID 2316101 reaction equation
[CH3:30][CH2:31][N:32]([CH2:33][CH3:34])[CH2:35][CH3:36].[CH3:50][N:51]([CH3:52])[CH:53]=[O:54].[Cl:37][C:38](=[O:39])[c:40]1[cH:41][cH:42][cH:43][cH:44][c:45]1[Cl:46].[Cl:47][CH2:48][Cl:49].[ClH:1].[n:2]1[cH:3][cH:4][c:5]([N:8]2[CH2:9][CH2:10][C:11]3([CH2:12][CH2:13][N:14]([C:17](=[O:18])[c:19]4[cH:20][c:21]5[c:26]([s:27]4)[CH2:25][CH2:24][NH:23][CH2:22]5)[CH2:15][CH2:16]3)[CH2:28][CH2:29]2)[cH:6][cH:7]1>>[n:2]1[cH:3][cH:4][c:5]([N:8]2[CH2:9][CH2:10][C:11]3([CH2:12][CH2:13][N:14]([C:17](=[O:18])[c:19]4[cH:20][c:21]5[c:26]([s:27]4)[CH2:25][CH2:24][N:23]([C:38](=[O:39])[c:40]4[cH:41][cH:42][cH:43][cH:44][c:45]4[Cl:46])[CH2:22]5)[CH2:15][CH2:16]3)[CH2:28][CH2:29]2)[cH:6][cH:7]1

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 6228DimethylformamideHCID 6344DichloromethaneHCID 8471TriethylamineHCID 691102-Chlorobenzoyl chlorideHCID 59483847HCID 59483847, compound

Product 1

HCID 46897096(5-(2-Chlorobenzoyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)(9-(pyridin-4-yl)-3,9-diazaspiro[5.5]undecan-3-yl)methanone

Sources & evidence

ORD record
ord-6f149471320e425085c04b52a2b33f28
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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