Hydroxide → 4-((6,7-Dimethoxyquinolin-4-yl)oxy)-3-fluorobenzenamine

HRID 2317537Notes

Reaction equation

HRID 2317537 reaction equation
[C:40]([O:41][CH2:42][CH3:43])(=[O:44])[CH3:45].[CH2:28]([N:29]([CH2:30][CH3:31])[CH2:32][CH3:33])[CH3:34].[CH3:35][N:36]([CH3:37])[CH:38]=[O:39].[F:1][c:2]1[c:3]([O:4][c:5]2[cH:6][cH:7][n:8][c:9]3[cH:10][c:11]([O:17][CH3:18])[c:12]([O:15][CH3:16])[cH:13][c:14]23)[cH:19][cH:20][c:21]([N+:23]([O-:24])=[O:25])[cH:22]1.[H:26][H:27].[OH-:46].[OH-:48].[Pd+2:47]>>[F:1][c:2]1[c:3]([O:4][c:5]2[cH:6][cH:7][n:8][c:9]3[cH:10][c:11]([O:17][CH3:18])[c:12]([O:15][CH3:16])[cH:13][c:14]23)[cH:19][cH:20][c:21]([NH2:23])[cH:22]1

Participants

8

Reactant 7

HCID 961Hydroxide2×HCID 6228DimethylformamideHCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 114507634-(2-Fluoro-4-nitrophenoxy)-6,7-dimethoxyquinolineHCID 178418361HCID 178418361, compound

Product 1

HCID 114269974-((6,7-Dimethoxyquinolin-4-yl)oxy)-3-fluorobenzenamine

Sources & evidence

ORD record
ord-779b7c91046d47c580fceda266945163
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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