Dimethylformamide → 2-Bromo-5-trimethylsilanylethynyl-pyrazine
Reaction equation
[Br:1][c:2]1[n:3][cH:4][c:5]([I:8])[n:6][cH:7]1.[C:9](#[CH:10])[Si:11]([CH3:12])([CH3:13])[CH3:14].[CH3:99][CH2:100][N:101]([CH2:102][CH3:103])[CH2:104][CH3:105].[Cu:16].[O:94]=[CH:95][N:96]([CH3:97])[CH3:98].[Pd:15].[cH:17]1[cH:18][cH:19][c:20]([P:21]([Pd:22]([P:23]([c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)([c:30]2[cH:31][cH:32][cH:33][cH:34][cH:35]2)[c:36]2[cH:37][cH:38][cH:39][cH:40][cH:41]2)([P:42]([c:43]2[cH:44][cH:45][cH:46][cH:47][cH:48]2)([c:49]2[cH:50][cH:51][cH:52][cH:53][cH:54]2)[c:55]2[cH:56][cH:57][cH:58][cH:59][cH:60]2)[P:61]([c:62]2[cH:63][cH:64][cH:65][cH:66][cH:67]2)([c:68]2[cH:69][cH:70][cH:71][cH:72][cH:73]2)[c:74]2[cH:75][cH:76][cH:77][cH:78][cH:79]2)([c:80]2[cH:81][cH:82][cH:83][cH:84][cH:85]2)[c:86]2[cH:87][cH:88][cH:89][cH:90][cH:91]2)[cH:92][cH:93]1>>[Br:1][c:2]1[n:3][cH:4][c:5]([C:10]#[C:9][Si:11]([CH3:12])([CH3:13])[CH3:14])[n:6][cH:7]1Participants
8
Sources & evidence
- ORD record
- ord-743cbcdfe0694e81af73b6781a56fab3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
Loading…