Water → N1-(3-Fluoro-4-(2-(1-methyl-1H-imidazol-2-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-N3-methyl-N3-phenylmalonamide
Reaction equation
[CH3:25][N:26]([C:27]([CH2:28][C:29](=[O:30])[OH:31])=[O:32])[c:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1.[CH3:53][CH2:54][O:55][C:56]([CH3:57])=[O:58].[CH:39]([N:40]([CH2:41][CH3:42])[CH:43]([CH3:44])[CH3:45])([CH3:46])[CH3:47].[F:1][c:2]1[cH:3][c:4]([NH2:24])[cH:5][cH:6][c:7]1[O:8][c:9]1[c:10]2[c:11]([n:12][cH:13][cH:14]1)[cH:15][c:16](-[c:18]1[n:19]([CH3:23])[cH:20][cH:21][n:22]1)[s:17]2.[O:48]=[CH:49][N:50]([CH3:51])[CH3:52].[OH2:59]>>[F:1][c:2]1[cH:3][c:4]([NH:24][C:29]([CH2:28][C:27]([N:26]([CH3:25])[c:33]2[cH:34][cH:35][cH:36][cH:37][cH:38]2)=[O:32])=[O:30])[cH:5][cH:6][c:7]1[O:8][c:9]1[c:10]2[c:11]([n:12][cH:13][cH:14]1)[cH:15][c:16](-[c:18]1[n:19]([CH3:23])[cH:20][cH:21][n:22]1)[s:17]2Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-62d3ca695eea4ec3b57a1166ab29e79a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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