Hydrochloric Acid → N-(4-tert-Butyl-6-methyl-pyridin-2-yl)-2-[2-fluoro-4-(7-pyridin-4-yl-imidazo[1,2-a]pyridin-3-yl)-phenyl]-acetamide

HRID 2319359Notes

Reaction equation

HRID 2319359 reaction equation
[C:29]([CH3:30])([CH3:31])([CH3:32])[c:33]1[cH:34][c:35]([NH2:40])[n:36][c:37]([CH3:39])[cH:38]1.[CH:65]([N:66]([CH:67]([CH3:68])[CH3:69])[CH2:70][CH3:71])([CH3:72])[CH3:73].[ClH:1].[ClH:2].[F:3][c:4]1[c:5]([CH2:25][C:26](=[O:27])[OH:28])[cH:6][cH:7][c:8](-[c:10]2[cH:11][n:12][c:13]3[n:14]2[cH:15][cH:16][c:17](-[c:19]2[cH:20][cH:21][n:22][cH:23][cH:24]2)[cH:18]3)[cH:9]1.[O:74]=[CH:75][N:76]([CH3:77])[CH3:78].[P-:41]([F:42])([F:43])([F:44])([F:45])([F:46])[F:47].[n:48]1([O:49][C:50]([N:51]([CH3:52])[CH3:53])=[N+:54]([CH3:55])[CH3:56])[c:57]2[n:58][cH:59][cH:60][cH:61][c:62]2[n:63][n:64]1>>[F:3][c:4]1[c:5]([CH2:25][C:26](=[O:28])[NH:40][c:35]2[cH:34][c:33]([C:29]([CH3:30])([CH3:31])[CH3:32])[cH:38][c:37]([CH3:39])[n:36]2)[cH:6][cH:7][c:8](-[c:10]2[cH:11][n:12][c:13]3[n:14]2[cH:15][cH:16][c:17](-[c:19]2[cH:20][cH:21][n:22][cH:23][cH:24]2)[cH:18]3)[cH:9]1

Participants

8

Reactant 7

HCID 313Hydrochloric Acid2×HCID 6228DimethylformamideHCID 9886HexafluorophosphateHCID 81531DiisopropylethylamineHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 685394014-(Tert-butyl)-6-methylpyridin-2-amineHCID 685432612-[2-Fluoro-4-(7-pyridin-4-ylimidazo[1,2-a]pyridin-3-yl)phenyl]acetic acid

Product 1

HCID 68543208N-(4-tert-Butyl-6-methyl-pyridin-2-yl)-2-[2-fluoro-4-(7-pyridin-4-yl-imidazo[1,2-a]pyridin-3-yl)-phenyl]-acetamide

Sources & evidence

ORD record
ord-af5638fdca3843328c964adb9a46bdc5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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