Hydrochloric Acid → 5-(1-Isopropyl-piperidin-4-yloxy)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic Acid 4-fluoro-benzylamide
Reaction equation
[B-:24]([F:25])([F:26])([F:27])[F:28].[CH:2]([CH3:3])([CH3:4])[N:5]1[CH2:6][CH2:7][CH:8]([O:11][c:12]2[cH:13][c:14]3[c:15]([n:16][cH:17]2)[nH:18][c:19]([C:21](=[O:22])[OH:23])[cH:20]3)[CH2:9][CH2:10]1.[CH:55]([N:56]([CH2:57][CH3:58])[CH:59]([CH3:60])[CH3:61])([CH3:62])[CH3:63].[ClH:1].[F:46][c:47]1[cH:48][cH:49][c:50]([CH2:51][NH2:52])[cH:53][cH:54]1.[O:64]=[CH:65][N:66]([CH3:67])[CH3:68].[n:29]1([O:30][C:31]([N:32]([CH3:33])[CH3:34])=[N+:35]([CH3:36])[CH3:37])[c:38]2[cH:39][cH:40][cH:41][cH:42][c:43]2[n:44][n:45]1>>[CH:2]([CH3:3])([CH3:4])[N:5]1[CH2:6][CH2:7][CH:8]([O:11][c:12]2[cH:13][c:14]3[c:15]([n:16][cH:17]2)[nH:18][c:19]([C:21](=[O:22])[NH:52][CH2:51][c:50]2[cH:49][cH:48][c:47]([F:46])[cH:54][cH:53]2)[cH:20]3)[CH2:9][CH2:10]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-ee5e7a9d208340b8a5c661037b82e7a7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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