Diisopropylamine → HCID 90728241, compound

HRID 2320952Notes

Reaction equation

HRID 2320952 reaction equation
[CH2:1]([C:2]#[CH:3])[N:4]1[CH2:5][CH2:6][CH:7]([CH2:10][OH:11])[CH2:8][CH2:9]1.[CH:12]([NH:13][CH:14]([CH3:15])[CH3:16])([CH3:17])[CH3:18].[Cl:19][c:20]1[cH:21][cH:22][c:23]([C:26](=[CH:27][CH2:28][O:29][c:30]2[cH:31][c:32]([CH3:42])[c:33]([O:34][CH2:35][C:36](=[O:37])[O:38][CH3:39])[cH:40][cH:41]2)[c:43]2[cH:44][cH:45][c:46]([I:49])[cH:47][cH:48]2)[cH:24][cH:25]1.[Cu:96][I:97].[O:50]1[CH2:51][CH2:52][CH2:53][CH2:54]1.[Pd:55]([Cl:56])[Cl:57].[c:58]1([P:59]([c:60]2[cH:61][cH:62][cH:63][cH:64][cH:65]2)[c:66]2[cH:67][cH:68][cH:69][cH:70][cH:71]2)[cH:72][cH:73][cH:74][cH:75][cH:76]1.[c:77]1([P:78]([c:79]2[cH:80][cH:81][cH:82][cH:83][cH:84]2)[c:85]2[cH:86][cH:87][cH:88][cH:89][cH:90]2)[cH:91][cH:92][cH:93][cH:94][cH:95]1>>[CH2:1]([C:2]#[C:3][c:46]1[cH:45][cH:44][c:43]([C:26]([c:23]2[cH:22][cH:21][c:20]([Cl:19])[cH:25][cH:24]2)=[CH:27][CH2:28][O:29][c:30]2[cH:31][c:32]([CH3:42])[c:33]([O:34][CH2:35][C:36](=[O:37])[O:38][CH3:39])[cH:40][cH:41]2)[cH:48][cH:47]1)[N:4]1[CH2:5][CH2:6][CH:7]([CH2:10][OH:11])[CH2:8][CH2:9]1

Participants

8

Reactant 7

HCID 7912DiisopropylamineHCID 8028TetrahydrofuranHCID 11776Triphenylphosphine2×HCID 24290Palladium ChlorideHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 18616662(1-(Prop-2-yn-1-yl)piperidin-4-yl)methanolHCID 91352668HCID 91352668, compound

Product 1

HCID 90728241HCID 90728241, compound

Sources & evidence

ORD record
ord-a420005cc1d1453d9f4af595804ed4c5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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