1,2-Dichloroethane → 3-Benzyloxy-N-(4-fluorobenzyl)-5-methyl-4-oxo-7-phenyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxamide

HRID 2321269Notes

Reaction equation

HRID 2321269 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([C:26](=[O:27])[OH:28])[n:11][n:12]2[c:13]1[C:14](=[O:25])[N:15]([CH3:24])[CH2:16][CH:17]2[c:18]1[cH:19][cH:20][cH:21][cH:22][cH:23]1.[CH2:39]([Cl:40])[CH2:41][Cl:42].[CH3:43][CH2:44][N:45]([CH2:46][CH3:47])[CH2:48][CH3:49].[F:50][c:51]1[cH:52][cH:53][c:54]([CH2:55][NH2:56])[cH:57][cH:58]1.[O:59]=[CH:60][N:61]([CH3:62])[CH3:63].[OH:29][n:30]1[c:31]2[c:32]([cH:33][cH:34][cH:35][cH:36]2)[n:37][n:38]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([C:26](=[O:28])[NH:56][CH2:55][c:54]2[cH:53][cH:52][c:51]([F:50])[cH:58][cH:57]2)[n:11][n:12]2[c:13]1[C:14](=[O:25])[N:15]([CH3:24])[CH2:16][CH:17]2[c:18]1[cH:19][cH:20][cH:21][cH:22][cH:23]1

Participants

7

Reactant 6

HCID 111,2-DichloroethaneHCID 6228DimethylformamideHCID 8471TriethylamineHCID 673264-FluorobenzylamineHCID 757711-HydroxybenzotriazoleHCID 580097413-Benzyloxy-5-methyl-4-oxo-7-phenyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylic acid

Product 1

HCID 689517403-Benzyloxy-N-(4-fluorobenzyl)-5-methyl-4-oxo-7-phenyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxamide

Sources & evidence

ORD record
ord-b4f591bde8194b26a2d3c3fdf0eda1cb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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