Potassium Cation → 6-bromo-1-(4-fluoro-phenyl)-1H-indazole-4-carboxylic acid methyl ester

HRID 2321348Notes

Reaction equation

HRID 2321348 reaction equation
[C:15](=[O:16])([O-:17])[O-:18].[CH3:1][O:2][C:3](=[O:4])[c:5]1[c:6]2[cH:7][n:8][nH:9][c:10]2[cH:11][c:12]([Br:14])[cH:13]1.[CH3:35][CH2:36][O:37][C:38](=[O:39])[CH3:40].[Cu:41][I:42].[F:21][c:22]1[cH:23][cH:24][c:25]([I:28])[cH:26][cH:27]1.[K+:19].[K+:20].[O:29]=[CH:30][N:31]([CH3:32])[CH3:33].[OH2:34]>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[c:6]2[cH:7][n:8][n:9](-[c:25]3[cH:24][cH:23][c:22]([F:21])[cH:27][cH:26]3)[c:10]2[cH:11][c:12]([Br:14])[cH:13]1

Participants

9

Reactant 8

HCID 813Potassium Cation2×HCID 962WaterHCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 96054-FluoroiodobenzeneHCID 19660Carbonate IonHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24728062methyl 6-bromo-1H-indazole-4-carboxylate

Product 1

HCID 581387736-bromo-1-(4-fluoro-phenyl)-1H-indazole-4-carboxylic acid methyl ester

Sources & evidence

ORD record
ord-5bad5dfa7cc64e9b8e14c63ca03934c4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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