1,2-Dichloroethane → [4-[[(5-Fluoropyrimidin-2-yl)amino]methyl]piperidin-1-yl]-(2-phenylcyclopropyl)methanone
Reaction equation
[CH2:28]([Cl:29])[CH2:30][Cl:31].[CH3:47][CH2:48][O:49][C:50](=[O:51])[CH3:52].[F:1][c:2]1[cH:3][n:4][c:5]([NH:8][CH2:9][CH:10]2[CH2:11][CH2:12][NH:13][CH2:14][CH2:15]2)[n:6][cH:7]1.[O:42]=[CH:43][N:44]([CH3:45])[CH3:46].[OH:32][n:33]1[c:34]2[c:35]([cH:36][cH:37][cH:38][cH:39]2)[n:40][n:41]1.[c:16]1([CH:22]2[CH:23]([C:25](=[O:26])[OH:27])[CH2:24]2)[cH:17][cH:18][cH:19][cH:20][cH:21]1>>[F:1][c:2]1[cH:3][n:4][c:5]([NH:8][CH2:9][CH:10]2[CH2:11][CH2:12][N:13]([C:25]([CH:23]3[CH:22]([c:16]4[cH:17][cH:18][cH:19][cH:20][cH:21]4)[CH2:24]3)=[O:26])[CH2:14][CH2:15]2)[n:6][cH:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-2b117faa42054fd3814a3e290aead0a2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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