Hydrochloric Acid → Tert-butyl 4-(2-chlorobenzylcarbamoyl)-4-(hydroxymethyl)piperidine-1-carboxylate
Reaction equation
[BH4-:29].[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[CH3:37][OH:38].[Cl:1][c:2]1[c:3]([CH2:4][NH:5][C:6](=[O:7])[C:8]2([C:21](=[O:22])[O:23][CH3:24])[CH2:9][CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[cH:25][cH:26][cH:27][cH:28]1.[ClH:31].[Li+:30]>>[Cl:1][c:2]1[c:3]([CH2:4][NH:5][C:6](=[O:7])[C:8]2([CH2:21][OH:22])[CH2:9][CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[cH:25][cH:26][cH:27][cH:28]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-c5b9a361c19f4a768b5d32295f09ea32
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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