1,2-Dichloroethane → 4-chloro-N-({4-chloro-3-[(3-cyano-5-ethenylphenyl)oxy]-2-fluorophenyl}methyl)-1-({[2-(trimethylsilyl)ethyl]oxy}methyl)-1H-imidazole-5-carboxamide
Reaction equation
[CH2:49]([Cl:50])[CH2:51][Cl:52].[CH3:58][CH2:59][O:60][C:61]([CH3:62])=[O:63].[Cl:22][c:23]1[n:24][cH:25][n:26]([CH2:31][O:32][CH2:33][CH2:34][Si:35]([CH3:36])([CH3:37])[CH3:38])[c:27]1[C:28](=[O:29])[OH:30].[NH2:1][CH2:2][c:3]1[c:4]([F:21])[c:5]([O:10][c:11]2[cH:12][c:13]([C:14]#[N:15])[cH:16][c:17]([CH:19]=[CH2:20])[cH:18]2)[c:6]([Cl:9])[cH:7][cH:8]1.[O:53]=[CH:54][N:55]([CH3:56])[CH3:57].[OH:39][n:40]1[c:41]2[c:42]([cH:43][cH:44][cH:45][cH:46]2)[n:47][n:48]1>>[NH:1]([CH2:2][c:3]1[c:4]([F:21])[c:5]([O:10][c:11]2[cH:12][c:13]([C:14]#[N:15])[cH:16][c:17]([CH:19]=[CH2:20])[cH:18]2)[c:6]([Cl:9])[cH:7][cH:8]1)[C:28]([c:27]1[c:23]([Cl:22])[n:24][cH:25][n:26]1[CH2:31][O:32][CH2:33][CH2:34][Si:35]([CH3:36])([CH3:37])[CH3:38])=[O:29]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-a4ee1b41d6ed46b5937d5b8e6c1fba75
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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