Hydrochloric Acid → 1h-Pyrrolo[2,3-c]pyridine-5-carboxamide,1-[(2,4-difluorophenyl)methyl]-n-hydroxy-3-[(2-methoxyethoxy)methyl]-n-methyl-

HRID 2323111Notes

Reaction equation

HRID 2323111 reaction equation
[CH3:29][NH:30][OH:31].[CH3:37][CH2:38][O:39][C:40]([CH3:41])=[O:42].[ClH:28].[F:1][c:2]1[c:3]([CH2:4][n:5]2[cH:6][c:7]([CH2:17][O:18][CH2:19][CH2:20][O:21][CH3:22])[c:8]3[c:9]2[cH:10][n:11][c:12]([C:14](=[O:15])[OH:16])[cH:13]3)[cH:23][cH:24][c:25]([F:27])[cH:26]1.[O:32]=[CH:33][N:34]([CH3:35])[CH3:36]>>[F:1][c:2]1[c:3]([CH2:4][n:5]2[cH:6][c:7]([CH2:17][O:18][CH2:19][CH2:20][O:21][CH3:22])[c:8]3[c:9]2[cH:10][n:11][c:12]([C:14](=[O:16])[N:30]([CH3:29])[OH:31])[cH:13]3)[cH:23][cH:24][c:25]([F:27])[cH:26]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 11647MethylhydroxylamineHCID 598558181h-Pyrrolo[2,3-c]pyridine-5-carboxylic acid,1-[(2,4-difluorophenyl)methyl]-3-[(2-methoxyethoxy)methyl]-

Product 1

HCID 159570881h-Pyrrolo[2,3-c]pyridine-5-carboxamide,1-[(2,4-difluorophenyl)methyl]-n-hydroxy-3-[(2-methoxyethoxy)methyl]-n-methyl-

Sources & evidence

ORD record
ord-0525122571c14f76a3d9e6382444c5f2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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