Bromide ion → (4-Chloro-2,6-difluorophenyl)(cyclopropyl)methanol

HRID 2324814Notes

Reaction equation

HRID 2324814 reaction equation
[Br-:12].[CH3:18][CH2:19][O:20][C:21](=[O:22])[CH3:23].[CH3:24][CH2:25][O:26][CH2:27][CH3:28].[CH:13]1([Mg+:16])[CH2:14][CH2:15]1.[Cl:1][c:2]1[cH:3][c:4]([F:11])[c:5]([CH:6]=[O:7])[c:8]([F:10])[cH:9]1.[ClH:17].[O:29]1[CH2:30][CH2:31][CH2:32][CH2:33]1>>[Cl:1][c:2]1[cH:3][c:4]([F:11])[c:5]([CH:6]([OH:7])[CH:13]2[CH2:14][CH2:15]2)[c:8]([F:10])[cH:9]1

Participants

8

Reactant 7

HCID 259Bromide ionHCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 27735124-Chloro-2,6-difluorobenzaldehydeHCID 178507030HCID 178507030, compound

Product 1

HCID 58392245(4-Chloro-2,6-difluorophenyl)(cyclopropyl)methanol

Sources & evidence

ORD record
ord-ee5b14b2707a42bdbd71603ae67843ec
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

Loading…