Methanol → 8-(3-Chloropyridin-2-yl)-2-cyclohexyl-2,8-diazaspiro[4.5]decan-1-one
Reaction equation
[CH3:42][N:43]1[C:44](=[O:45])[CH2:46][CH2:47][CH2:48]1.[CH3:49][OH:50].[CH:1]1([N:7]2[C:8](=[O:17])[C:9]3([CH2:10][CH2:11]2)[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]3)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[CH:26]([N:27]([CH2:28][CH3:29])[CH:30]([CH3:31])[CH3:32])([CH3:33])[CH3:34].[Cl:18][c:19]1[n:20][cH:21][cH:22][cH:23][c:24]1[Cl:25].[OH:35][C:36]([C:37]([F:38])([F:39])[F:40])=[O:41]>>[CH:1]1([N:7]2[C:8](=[O:17])[C:9]3([CH2:10][CH2:11]2)[CH2:12][CH2:13][N:14]([c:19]2[n:20][cH:21][cH:22][cH:23][c:24]2[Cl:25])[CH2:15][CH2:16]3)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1Participants
7
Sources & evidence
- ORD record
- ord-798dd1d5303d478798f52a9c73d0f4d9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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